Tetraethyl Orthosilicate is a clear, colourless liquid that is pure and has low alcohol content. It is primarily used in the pharmaceutical industry. Some of its major applications are as a cross-linking agent, release controlling polymer and as a precursor to prepare silica xerogel which is used as a drug carrier in NDDS formulations. All our products are manufactured under the most stringent environment, health and safety standards. We comply with the Highest Quality Standards and are an ISO 9001:2015, 14001:2015, ISO 45001:2018, ISO/IEC 17025:2017, EXCiPACT and GMP certified company.
HP, USDMF
Applications
Tetraethyl Orthosilicate is widely used in the pharmaceutical industry and specially for application in Topical products (i.e. Transdermal patches). Following are few of the major applications,
General Information
Pharmacopeia Status : In-house product
CAS No. : 78-10-4
EC No. : 201-083-8
Appearance / Description : Clear colorless liquid
Molecular Formula : Si-C8H20O4
Molecular Mass : 208.33g/mol
Marketed Formulation
Multiple formulations are under R&D stage
Quality and Regulatory Support
Key Product Attributes
Pack Mode
DMF (Drug Master File)
USDMF registered product (DMF # 034762)
Product Specifications (In-house)
| Particulars | Limit |
|---|---|
| Appearance | Clear colorless liquid |
| Identification by (ATR – FTIR) | Infrared spectrum of test preparation should be concurrent with that of the TEOS reference standard or working standard preparation |
| Identification (By GC) | The retention time of the main peak of the sample solution corresponds to that of the reference solution and exhibit only one major peak corresponding to TEOS |
| Assay (By GC) | Not less than 98.0% w/w |
| Purity (By GC) | Not less than 98.0% |
| Hydrolysable Chloride | Less than 50 mg/kg |
| Ethanol Traces (by GC) | Not more than 1.0% |
Stability and Storage Conditions
Stable under recommended conditions. Storage should be in accordance with all current regulations and standards. Keep container tightly closed in a cool & dry area under inert atmosphere. Keep away from incompatible substances.
Safety and Handling Information
Handling of the product should be in accordance with all current regulations and standards Use spark-proof tools and explosion-proof equipment. Avoid breathing dust, vapour, mist or gas. Avoid contact with skin, eyes and take precautionary measures against static discharges.
