Propylene glycol USP/Ph.Eur 25LT Go Back


: 57-55-6

Molecular Formula

: C3H8O2

Molecular Weight

: 76.1
Description: Clear, colourless, viscous liquid having a slight, characteristic taste. Is practically odourless. Absorbs moisture when exposed to moist air.
Solubility: Miscible with water, with ethanol (96%), with acetone, and with chloroform Soluble in ether and will dissolve many essential oils, but is immiscible with fixed oils.
Identification (by IR): IR spectra of the sample should be concomitant with IR spectra of the standard
Identification (Diethylene glycol): NMT 0.10%
Identification (Ethylene glycol): NMT 0.10%
Identification (By GC Chromatogram): The retention time of the propylene glycol peak of the sample solution corresponds to that of the standard solution
Identification (by Relative density, 20°C): 1.035 - 1.040
Identification (By Refractive index, 20±0.5°C): 1.431 - 1.433
Identification (By Boiling Point): 184° - 189°C
Identification (By Melting point): Crystals should melt between 121 °C to 128 °C.
Specific gravity, 25°C: 1.035 - 1.037
Relative density, 20°C: 1.035 - 1.040
Refractive index (20°C ± 0.5°C): 1.431 - 1.433
Assay: NLT 99.5%
Residue on ignition: The weight of the residue is NMT 3.5 mg (0.007% max)
Chloride (Cl): 70ppm max
Sulphate (SO4): 60ppm max
Acidity: Not more than 0.05 mL of 0.1 M sodium hydroxide should require to change the colour of the indicator to blue.
Oxidising substances: Not more than 0.2 mL of 0.05 M sodium thiosulfate should require.
Reducing substances: The solution should not change its appearance.
Water: NMT 0.2%
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COA Product Catalogues Product Search Parenteral Applications