CASR |
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Molecular Formula |
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Molecular Weight |
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| Specifications | |
|---|---|
| Description: | Clear, colourless, syrupy liquid, unctuous to the touch, having a sweet taste. Has not more than a slight characteristic odor, which is neither harsh nor disagreeable. Is hygroscopic. Its solutions are neutral to litmus. |
| Solubility: | Miscible with water, ethanol (96%) and with alcohol. Slightly soluble in acetone. Insoluble in fatty oils, in essential oils, in chloroform, in ether and in fixed and volatile oils. |
| Identification (By IR): | IR spectra of the sample should be concomitant with IR spectra of the standard. |
| Identification (Diethylene glycol): | NMT 0.10% |
| Identification (Ethylene glycol): | NMT 0.10% |
| Identification (By GC Chromatogram): | The retention time of the glycerine peak of the Sample solution corresponds to that obtained in the Standard solution. |
| Identification 1 (By Chemical test): | Within 10 min, the blue colour does not diffuse into the lower layer. |
| Identification 2 (By Chemical test): | Vapours (acrolein) are evolved which blacken filter paper impregnated with alkaline potassium tetraiodomercurate solution. |
| Appearance of solution: | Clear and colorless solution. |
| Color: | The colour should not be darker than reference solution. |
| Acidity or alkalinity: | Pink colour should produce after adding 0.2 mL of 0.1 mol/L sodium hydroxide solution. |
| Refractive index, 20°C: | 1.470 - 1.475 |
| Relative density (20°C): | 1.258 - 1.268 |
| Aldehydes and reducing substances: | The light absorption of the test solution at 655 nm should not be more than that of 2.0 mL of the reference solution. |
| Fatty acids and esters: | NMT 2.0 mL of sodium hydroxide (0.1 mol/L) VS should require. |
| Related substances: Impurity A (Diethylene glycol): | NMT 0.1% |
| Related substances: Any other impurity with a retention time less than the retention time of glycerol: | NMT 0.1% |
| Related substances: Total of all impurities with retention times greater than the retention time of glycerol: | NMT 0.5% |
| Related substances: Individual impurity: | NMT 0.1% |
| Related substances: Total impurities: | NMT 1.0% |
| Halogenated compounds: | NMT 35 ppm |
| Sugars: | The solution should remain blue and no precipitate should form. |
| Chlorides: | NMT 0.0006% |
| Sulphate: | NMT 0.002% |
| Water: | NMT 2.0% |
| Residue on ignition: | NMT 0.01% |
| Assay (Anhydrous basis): | 99.0% - 101.0% |
| Chlorinated substances: | NMT 0.003% |
| Readily carbonizable substances: | Any colour produced should not more intense than that of an equal volume of a reference solution. |
| Ammonium: | No odour of ammonia should produced. |
| Calcium: | The solution should be clear. |
| Iron: | NMT 0.00005% |
| Total aerobic microbial count: | NMT 100 CFU/gm |
| Total combined yeast and mold count: | NMT 10 CFU/gm |
| E.coli: | Should not be detected. |
