Dimethyl sulphoxide USP/Ph.Eur PARENTEX 190LT Go Back


: 67-68-5

Molecular Formula

: C2H6OS

Molecular Weight

: 78.13
Appearance/Description: A clear, colorless, odorless, hygroscopic liquid or crystals. Melts about 18.4°C. Boils at about 189°C.
Solubility: Soluble in water. Miscible with ethanol ; practically insoluble in acetone ,in benzene, in chloroform and in ether.
Identification (By IR): IR spectra of the sample should be concomittant with IR pectra of the corresponding standard
Identification (By chemical test 1): A deep violet, crystalline solid should obtaine which should soluble in chloroform, yielding a red solution.
Identification (By chemical test 2): The colour changes to green or bluish-green. Cool.The colour changes to greenish-yellow.
Identification (by Relative density, 20°C): 1.100-1.104
Identification (By Refractive index, 20±0.5°C): 1.478-1.480
Specific gravity, 25°C: Between 1.095 to 1.101
Relative density,20°C: 1.100-1.104
Refractive index (20°C ± 0.5°C): 1.478-1.480
Refractive index, 25°C: 1.4755 - 1.4775
Freezing point: NLT 18.3°C
Acidity: Not more than 5.0ml of 0.01N sodium hydroxide should consume
Water: NMT 0.1%
UV absorbance profile (10mm cell)@270nm-350nm: The spectrum is smooth with no absorption maxima.
UV absorbance ratio (A285nm/A275nm): NMT 0.65
UV absorbance ratio (A295nm/A275nm): NMT 0.45
UV absorbance profile (10mm cell)@275nm: NMT 0.20
UV absorbance profile (10mm cell)@285nm: NMT 0.20
UV absorbance profile (10mm cell)@295nm: NMT 0.20
Limit of Non volatile residue: NMT 0.01%
Related compunds / Related substances - Total impurities: NMT 0.10%
Related substance (Unspecified impurities): NMT 0.10%
Assay (Anhydrous basis): NLT 99.9%
Total aerobic microbial count: NMT 1000 CFU/mL
Total Yeast and mold count: NMT 100 CFU/mL
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