Metacresol USP/Ph.Eur/BP PARENTEX PLUS 100ML Go Back


: 108-39-4

Molecular Formula


Molecular Weight

: 108.14
Description: Colourless or yellowish to brownish-yellow or pinkish, highly refrective liquid, becoming darker with age and on exposure to light.
Solubility: Sparingly soluble in water, usually forming a cloudy solution; dissolves in solutions of fixed alkali hydroxides. Miscible with alcohol, with ether, with glycerine,with ethanol (96%) and with methylene chloride.
Identification A (By IR): IR spectra of the sample should be concomitant with IR spectra of the corresponding standard.
Identification B (By GC Chromatogram): The retention time of the major peak of the sample solution corresponds to that of the standard solution, as obtained in the assay.
Relative density: About 1.03
Melting point: About 11 °C
Boiling point: About 202 °C
Appearance of Solution: Freshly prepared solution should not more opalescent than reference suspension III and not more intensely coloured than reference solution BY7.
Assay (By GC): 98.0% - 102.0%
Organic Impurities / Related substances (Orthocresol): NMT 0.5%
Organic Impurities / Related substances (Paracresol): NMT 0.3%
Organic Impurities/ Related substances (Any unspecified impurity): NMT 0.1%
Organic Impurities / Related substances (Total impurities): NMT 1.0%
Clarity of Solution A (By Chemical Test): A clear solution
Clarity of Solution B (By Chemical Test): A clear solution
Acidity: Not more than 0.5mL of 0.01 M sodium hydroxide should require to change the colour of the indicator to yellow.
Residue on evaporation: NMT 0.1%
Absorption (400-700 nm): NMT 0.05
Toluene content (By GC): NMT 100ppm
Bacterial endotoxins: NMT 0.1 EU/mg
Total aerobic microbial count: NMT 100 CFU/gm
Total Yeast and mold count: NMT 10 CFU/gm
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